Discoveries and Data: Specific Conditions

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title_bd_clefts_racial-4126704

To describe racial/ethnic patterns in oral cleft occurrence, we looked at over 3,800 infants with oral clefts drawn from 2.2 million California births.

bullet-1043296 Blacks had lower rates of oral clefts compared to Whites. For cleft lip with/without cleft palate, the difference was mainly in cases with no associated birth defects. In cleft palate, there was a reduction across all subtypes.
bullet-1043296 Hispanics had a lower rate of cleft palate compared to Whites, both for isolated clefts and clefts occurring as part of birth defects sequences.
bullet-1043296 Relative to their US-born counterparts, the risk of cleft lip with/without cleft palate was slightly lower among the offspring of foreign-born Chinese women. Oral clefts were slightly higher among foreign-born Filipinas. However, data is fairly sparse in these groups and differences may simply be due to chance.

Racial/ethnic differences may be caused by genetic variation across groups. Cultural practices—including diet and other habits—may influence environmental exposures during pregnancy.

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