To describe racial/ethnic patterns in oral cleft occurrence, we looked at over 3,800 infants with oral clefts drawn from 2.2 million California births.
|Blacks had lower rates of oral clefts compared to Whites. For cleft lip with/without cleft palate, the difference was mainly in cases with no associated birth defects. In cleft palate, there was a reduction across all subtypes.|
|Hispanics had a lower rate of cleft palate compared to Whites, both for isolated clefts and clefts occurring as part of birth defects sequences.|
|Relative to their US-born counterparts, the risk of cleft lip with/without cleft palate was slightly lower among the offspring of foreign-born Chinese women. Oral clefts were slightly higher among foreign-born Filipinas. However, data is fairly sparse in these groups and differences may simply be due to chance.|
Racial/ethnic differences may be caused by genetic variation across groups. Cultural practices—including diet and other habits—may influence environmental exposures during pregnancy.
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